Using a graded repair methodology, the chance of a post-operative CSF leak is generally 1% or less for standard endonasal removal of pituitary adenomas and other sellar tumors (Grade 1 and 2 CSF leaks and skull base defects) but is increased to 3-5% for large skull base defects (Grade 3) associated with endoscopic endonasal removal of brain tumors such as craniopharyngiomas, meningiomas and some very large invasive pituitary adenomas. If the membrane that surrounds the brain and spinal cord tears or punctures, spinal fluid (or its medical term, cerebrospinal fluid CSF) contained by. Schwalje, MD, DMA 1 Megan Jensen, MD 1 et al Luyuan Li, MD 1 Brian J. The extent and type of skull base repair depends on the size and location of the defect. Cerebrospinal Fluid Leak After Nasal Swab Testing for Coronavirus Disease 2019 Christopher Blake Sullivan, MD 1 Adam T. Kelly’s Recent Experience, CSF leaks that occur at the time of surgery require careful repair to avoid a post-operative CSF leak. One of the more common complications of endonasal transsphenoidal surgery is a post-operative CSF leak. This is a potentially dangerous condition that can lead to an infection of the CSF (meningitis) or of the brain itself (brain abscess). On occasion, as a result of a skull fracture, weakness of the brain covering (dura), intracranial surgery or growth of a brain tumor, CSF may leak through the brain covering. Pacific Neuroscience Institute DirectoryĬerebrospinal fluid (CSF) is constantly made by the brain and reabsorbed into the blood system.Providence Holy Cross Medical Center Mission Hills. ![]()
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